Reticular erythematous mucinosis: a review of patients' characteristics, associated conditions, therapy and outcome in 25 cases
Identifieur interne : 001177 ( Main/Exploration ); précédent : 001176; suivant : 001178Reticular erythematous mucinosis: a review of patients' characteristics, associated conditions, therapy and outcome in 25 cases
Auteurs : F. Rongioletti [Italie] ; V. Merlo [Italie] ; S. Riva [Italie] ; E. Cozzani [Italie] ; E. Cinotti [Italie] ; G. Ghigliotti [Italie] ; A. Parodi [Italie] ; J. Kanitakis [France]Source :
- British Journal of Dermatology [ 0007-0963 ] ; 2013-12.
English descriptors
- Teeft :
- Antimalarial, Arch dermatol, British association, British journal, Carcinoma, Complete remission, Contraceptive, Contraceptive pill, Cutaneous, Cutaneous lupus erythematosus, Dermatol, Dermatology, Dermoepidermal junction, Erythematosus, Erythematous, Erythematous macules, Histopathological, Lesion, Lupus, Lupus erythematosus, Mucin, Mucinosis, Neck chest, Other conditions, Possible association, Recognizable disease, Reticular, Reticular erythematous mucinosis, Reticular pattern, Reticulated patterns, Rongioletti, Skin lesions, Thyroid dysfunctions, Upper abdomen.
Abstract
Background: Reticular erythematous mucinosis (REM) is an uncommon disease, the nosology and specific characteristics of which are controversial because most reports deal with single cases or small series. Objectives: To describe the characteristics of patients with REM regarding demographics, clinical and pathological features, comorbidities, treatment and course. Methods: A retrospective and prospective study was conducted on 25 patients diagnosed with REM in the setting of university‐affiliated dermatology departments and dermatopathology centres. Results: Of the 25 patients with REM, 16 were women (sex ratio 2 : 1) and the mean age was 46 years. The roles of sun exposure and oral contraceptives were ambiguous. Associated diseases included hypertension (n = 4), malignancies (n = 3), autoimmune diseases (n = 3) and Borrelia infection (n = 1). Immunological studies (including serology and direct immunofluorescence) were noncontributory. The response to antimalarial treatment was good in > 80% of cases. Worsening or recurrence of the lesion after treatment discontinuation, or in the course of the disease, occurred in 31% of patients. Conclusions: We present the largest REM case series to date. The reticular pattern with involvement of the midline of the chest and back, the predilection for middle‐aged women, the controversial relationship with photosensitivity and the possible association with other conditions such as malignancies and thyroid dysfunctions are the main characteristics that makes REM a recognizable disease.
What's already known about this topic? Reticular erythematous mucinosis (REM) is an uncommon disease, the nosology and specific characteristics of which are controversial because most reports deal with single cases or small series. What does this study add? We report one of the largest case series of REM to date. We highlight the reticular pattern in REM; the predilection for middle‐aged women; the ambiguous role of photosensitivity; the possible association with other conditions such as malignancies and thyroid dysfunctions; and the good response to antimalarials, with possible relapses. Together, these factors make REM a recognizable disease.
Url:
DOI: 10.1111/bjd.12577
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000128
- to stream Istex, to step Curation: 000128
- to stream Istex, to step Checkpoint: 000229
- to stream Main, to step Merge: 001178
- to stream Main, to step Curation: 001177
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Reticular erythematous mucinosis: a review of patients' characteristics, associated conditions, therapy and outcome in 25 cases</title><author><name sortKey="Rongioletti, F" sort="Rongioletti, F" uniqKey="Rongioletti F" first="F." last="Rongioletti">F. Rongioletti</name></author><author><name sortKey="Merlo, V" sort="Merlo, V" uniqKey="Merlo V" first="V." last="Merlo">V. Merlo</name></author><author><name sortKey="Riva, S" sort="Riva, S" uniqKey="Riva S" first="S." last="Riva">S. Riva</name></author><author><name sortKey="Cozzani, E" sort="Cozzani, E" uniqKey="Cozzani E" first="E." last="Cozzani">E. Cozzani</name></author><author><name sortKey="Cinotti, E" sort="Cinotti, E" uniqKey="Cinotti E" first="E." last="Cinotti">E. Cinotti</name></author><author><name sortKey="Ghigliotti, G" sort="Ghigliotti, G" uniqKey="Ghigliotti G" first="G." last="Ghigliotti">G. Ghigliotti</name></author><author><name sortKey="Parodi, A" sort="Parodi, A" uniqKey="Parodi A" first="A." last="Parodi">A. Parodi</name></author><author><name sortKey="Kanitakis, J" sort="Kanitakis, J" uniqKey="Kanitakis J" first="J." last="Kanitakis">J. Kanitakis</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:1CDDEB60FCB204EA05927C12B442160C9B4CCF3B</idno><date when="2013" year="2013">2013</date><idno type="doi">10.1111/bjd.12577</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-PN597WBJ-3/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000128</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000128</idno><idno type="wicri:Area/Istex/Curation">000128</idno><idno type="wicri:Area/Istex/Checkpoint">000229</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000229</idno><idno type="wicri:doubleKey">0007-0963:2013:Rongioletti F:reticular:erythematous:mucinosis</idno><idno type="wicri:Area/Main/Merge">001178</idno><idno type="wicri:Area/Main/Curation">001177</idno><idno type="wicri:Area/Main/Exploration">001177</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Reticular erythematous mucinosis: a review of patients' characteristics, associated conditions, therapy and outcome in 25 cases</title><author><name sortKey="Rongioletti, F" sort="Rongioletti, F" uniqKey="Rongioletti F" first="F." last="Rongioletti">F. Rongioletti</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Dermatology, Department of Health Sciences (DISSAL), University of Genoa, Viale Benedetto XV, 16132, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation><affiliation></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Italie</country></affiliation></author><author><name sortKey="Merlo, V" sort="Merlo, V" uniqKey="Merlo V" first="V." last="Merlo">V. Merlo</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Dermatology, Department of Health Sciences (DISSAL), University of Genoa, Viale Benedetto XV, 16132, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Riva, S" sort="Riva, S" uniqKey="Riva S" first="S." last="Riva">S. Riva</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Dermatology, Department of Health Sciences (DISSAL), University of Genoa, Viale Benedetto XV, 16132, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Cozzani, E" sort="Cozzani, E" uniqKey="Cozzani E" first="E." last="Cozzani">E. Cozzani</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Dermatology, Department of Health Sciences (DISSAL), University of Genoa, Viale Benedetto XV, 16132, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Cinotti, E" sort="Cinotti, E" uniqKey="Cinotti E" first="E." last="Cinotti">E. Cinotti</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Dermatology, Department of Health Sciences (DISSAL), University of Genoa, Viale Benedetto XV, 16132, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Ghigliotti, G" sort="Ghigliotti, G" uniqKey="Ghigliotti G" first="G." last="Ghigliotti">G. Ghigliotti</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Dermatology, Department of Health Sciences (DISSAL), University of Genoa, Viale Benedetto XV, 16132, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Parodi, A" sort="Parodi, A" uniqKey="Parodi A" first="A." last="Parodi">A. Parodi</name><affiliation wicri:level="1"><country xml:lang="fr">Italie</country><wicri:regionArea>Section of Dermatology, Department of Health Sciences (DISSAL), University of Genoa, Viale Benedetto XV, 16132, Genoa</wicri:regionArea><wicri:noRegion>Genoa</wicri:noRegion></affiliation></author><author><name sortKey="Kanitakis, J" sort="Kanitakis, J" uniqKey="Kanitakis J" first="J." last="Kanitakis">J. Kanitakis</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Ed. Herriot Hospital Group, 5 Place d'Arsonval, 69437, Lyon</wicri:regionArea><placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">British Journal of Dermatology</title><title level="j" type="alt">BRITISH JOURNAL OF DERMATOLOGY</title><idno type="ISSN">0007-0963</idno><idno type="eISSN">1365-2133</idno><imprint><biblScope unit="vol">169</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="1207">1207</biblScope><biblScope unit="page" to="1211">1211</biblScope><biblScope unit="page-count">5</biblScope><date type="published" when="2013-12">2013-12</date></imprint><idno type="ISSN">0007-0963</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0007-0963</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Antimalarial</term><term>Arch dermatol</term><term>British association</term><term>British journal</term><term>Carcinoma</term><term>Complete remission</term><term>Contraceptive</term><term>Contraceptive pill</term><term>Cutaneous</term><term>Cutaneous lupus erythematosus</term><term>Dermatol</term><term>Dermatology</term><term>Dermoepidermal junction</term><term>Erythematosus</term><term>Erythematous</term><term>Erythematous macules</term><term>Histopathological</term><term>Lesion</term><term>Lupus</term><term>Lupus erythematosus</term><term>Mucin</term><term>Mucinosis</term><term>Neck chest</term><term>Other conditions</term><term>Possible association</term><term>Recognizable disease</term><term>Reticular</term><term>Reticular erythematous mucinosis</term><term>Reticular pattern</term><term>Reticulated patterns</term><term>Rongioletti</term><term>Skin lesions</term><term>Thyroid dysfunctions</term><term>Upper abdomen</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Background: Reticular erythematous mucinosis (REM) is an uncommon disease, the nosology and specific characteristics of which are controversial because most reports deal with single cases or small series. Objectives: To describe the characteristics of patients with REM regarding demographics, clinical and pathological features, comorbidities, treatment and course. Methods: A retrospective and prospective study was conducted on 25 patients diagnosed with REM in the setting of university‐affiliated dermatology departments and dermatopathology centres. Results: Of the 25 patients with REM, 16 were women (sex ratio 2 : 1) and the mean age was 46 years. The roles of sun exposure and oral contraceptives were ambiguous. Associated diseases included hypertension (n = 4), malignancies (n = 3), autoimmune diseases (n = 3) and Borrelia infection (n = 1). Immunological studies (including serology and direct immunofluorescence) were noncontributory. The response to antimalarial treatment was good in > 80% of cases. Worsening or recurrence of the lesion after treatment discontinuation, or in the course of the disease, occurred in 31% of patients. Conclusions: We present the largest REM case series to date. The reticular pattern with involvement of the midline of the chest and back, the predilection for middle‐aged women, the controversial relationship with photosensitivity and the possible association with other conditions such as malignancies and thyroid dysfunctions are the main characteristics that makes REM a recognizable disease.</div><div type="abstract" xml:lang="en">What's already known about this topic? Reticular erythematous mucinosis (REM) is an uncommon disease, the nosology and specific characteristics of which are controversial because most reports deal with single cases or small series. What does this study add? We report one of the largest case series of REM to date. We highlight the reticular pattern in REM; the predilection for middle‐aged women; the ambiguous role of photosensitivity; the possible association with other conditions such as malignancies and thyroid dysfunctions; and the good response to antimalarials, with possible relapses. Together, these factors make REM a recognizable disease.</div></front></TEI><affiliations><list><country><li>France</li><li>Italie</li></country><region><li>Auvergne-Rhône-Alpes</li><li>Rhône-Alpes</li></region><settlement><li>Lyon</li></settlement></list><tree><country name="Italie"><noRegion><name sortKey="Rongioletti, F" sort="Rongioletti, F" uniqKey="Rongioletti F" first="F." last="Rongioletti">F. Rongioletti</name></noRegion><name sortKey="Cinotti, E" sort="Cinotti, E" uniqKey="Cinotti E" first="E." last="Cinotti">E. Cinotti</name><name sortKey="Cozzani, E" sort="Cozzani, E" uniqKey="Cozzani E" first="E." last="Cozzani">E. Cozzani</name><name sortKey="Ghigliotti, G" sort="Ghigliotti, G" uniqKey="Ghigliotti G" first="G." last="Ghigliotti">G. Ghigliotti</name><name sortKey="Merlo, V" sort="Merlo, V" uniqKey="Merlo V" first="V." last="Merlo">V. Merlo</name><name sortKey="Parodi, A" sort="Parodi, A" uniqKey="Parodi A" first="A." last="Parodi">A. Parodi</name><name sortKey="Riva, S" sort="Riva, S" uniqKey="Riva S" first="S." last="Riva">S. Riva</name><name sortKey="Rongioletti, F" sort="Rongioletti, F" uniqKey="Rongioletti F" first="F." last="Rongioletti">F. Rongioletti</name></country><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Kanitakis, J" sort="Kanitakis, J" uniqKey="Kanitakis J" first="J." last="Kanitakis">J. Kanitakis</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001177 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001177 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:1CDDEB60FCB204EA05927C12B442160C9B4CCF3B
|texte= Reticular erythematous mucinosis: a review of patients' characteristics, associated conditions, therapy and outcome in 25 cases
}}
| This area was generated with Dilib version V0.6.33. |  |